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Solved2.09K viewsDrug Dose Adjustment

Some physicians ask for Slou Cortef q 12 hr, is it correct with its short duration of action compared to dexamethasone?

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Usually, Hydrocortisone interval is 6 to 8 hours, however some limited data available for 12 hr interval:

1 to 5 mg/kg/day or 30 to 150 mg/m2/day divided every 12 to 24 hours

(Kliegman 2007)

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