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Solved195 viewsDrug Preparation, Storage and Stability

In EMC reference, Vancomycin is sensitive to light, if that is correct, why all Vancomycin available in market is in a transparent vials?

Hossam Elgnainy Selected answer as best March 5, 2025
1

The best source to take storage precautions is the pamphlet as it may differ from product to product.

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Regarding light sensitivity of Injectable drugs, you should know that the light sensitivity can be different according to the phase of preparation, generally 4 phases that can has different light stability.

1. During the storage of the vial

2. After reconstitution

3. After dilution

4. During administration

You should know that the sensitivity to light can be different on every phase.

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The fact that the vial is transparent means nothing as it, anyways, enclosed inside a dark carton pack.

Hossam Elgnainy Selected answer as best March 5, 2025

University of Illinois at Chicago College of Pharmacy, Drug Information Group*. Light-sensitive injectable prescription drugs. Hosp Pharm. 2014 Feb;49(2):136-63. doi: 10.1310/hpj4902-136. PMID: 24623868; PMCID: PMC3940680.

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