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In case of resistant fever in PICU, is it OK to use NSAIDs in alternative to paracetamol to control it?
Yes, NSAIDs can be used as an alternative to paracetamol for fever control in the PICU if benefits outweigh the risks. However, a case-by-case assessment is crucial, and treating the underlying cause of fever remains the priority.
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Considerations before NSAID use:
1. Renal function: NSAIDs can reduce renal perfusion, especially in hypovolemic or critically ill children.
2. Platelet function and bleeding risk: NSAIDs can impair platelet aggregation.
3. GI protection: Consider PPIs if prolonged NSAID use is necessary.
4. Hepatic status: While paracetamol is hepatically metabolized, NSAIDs may be safer in liver-compromised patients if renal function is intact.
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Did you investigate the patient’s current medications? As some medications can cause fever as a side effect