بِسْمِ اللَّـهِ الرَّحْمَـٰنِ الرَّحِيمِ الَّذِي خَلَقَنِي فَهُوَ يَهْدِينِ وَالَّذِي هُوَ يُطْعِمُنِي وَيَسْقِينِ وَإِذَا مَرِضْتُ فَهُوَ يَشْفِينِ
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Levofloxacin cross BBB or not

can used for ttt meningitis or cns infection or not

Hossam Elgnainy Selected answer as best March 3, 2024
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Levofloxacin can cross to csf by 30-50 %

Levofloxacin can be used for Meningitis treatment as alternative agent (off-label use) in adults in combination with other appropriate agents for 2 to 3 weeks or until clinically stable, whichever is longer (CDC [Hendricks 2014]).

Hossam Elgnainy Selected answer as best March 3, 2024