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Cyclosporine

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Dose of cyclosporine in Steven Johnson Syndrome?

Hossam Elgnainy Selected answer as best February 19, 2024

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Hossam Elgnainy3.34K 1 Comment

3 mg/kg/d for 10 days,
then 2 mg/kg/d for 10 days,
and finally 1 mg/kg/d for 10 days

Ref:

Ng QX, De Deyn MLZQ, Venkatanarayanan N, Ho CYX, Yeo WS. A meta-analysis of cyclosporine treatment for Stevens-Johnson syndrome/toxic epidermal necrolysis. J Inflamm Res. 2018 Mar 28;11:135-142. doi: 10.2147/JIR.S160964. PMID: 29636627; PMCID: PMC5880515.

Hossam Elgnainy Selected answer as best February 19, 2024
Hossam Elgnainy commented

Some studies suggest 5 mg/kg/day