بِسْمِ اللَّـهِ الرَّحْمَـٰنِ الرَّحِيمِ الَّذِي خَلَقَنِي فَهُوَ يَهْدِينِ وَالَّذِي هُوَ يُطْعِمُنِي وَيَسْقِينِ وَإِذَا مَرِضْتُ فَهُوَ يَشْفِينِ
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Can clindamycin used for tretment complicated pneumonia with effusion or empyma with MRSA risk factor or vancomycin  preferred

Hossam Elgnainy Selected answer as best January 26, 2024
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Clindamycin is not a great option for Hospital Acquired MRSA and also is not a good option if the resistance rates are > 10% in the community or if the rates of resistance are unknown.
So, generally, I would recommend Vancomycin.

Hossam Elgnainy Selected answer as best January 26, 2024

However, Clindamycin can be used as add-on therapy to cover anaerobes and to treat toxic shock syndrome or prevent it.