Senior Clinical Pharmacist, Clinical Pharmacy Preceptor, Cairo University Specialized Pediatric Hospital (Abo-Elreesh Elyabany). Clinical Pharmacy Preceptor and Lecturer, General Organization For Teaching Hospitals and Institutes.
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May 14, 2025 10
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Since no effective antiviral therapy is available to you: Aggressive supportive care becomes the main way of treatment. Control fever Manage seizures Ensure proper hydration and electrolytes Respiratory...

May 14, 2025 2
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Adenovirus

Unfortunately, acyclovir is not effective against adenovirus

May 14, 2025 5
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Dexamethasone in RTA

in the pediatric setting, dexamethasone does not play a significant routine role in the acute management of children involved in road traffic accidents (RTAs): ... 1. Pediatric Traumatic Brain Injury (TBI):...

May 14, 2025 5
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NSAIDs in PICU

Yes, NSAIDs can be used as an alternative to paracetamol for fever control in the PICU if benefits outweigh the risks. However, a case-by-case assessment is crucial, and treating the underlying cause of...

May 14, 2025 5
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May 14, 2025 10
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Typical dos of l- carnitine 50 mg/kg/day in divided doses; may titrate slowly as needed to 100 mg/kg/day in divided doses Max dose 3000mg/day

May 13, 2025 2
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Did you investigate the patient's current medications? As some medications can cause fever as a side effect

May 13, 2025 2
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Most safe choice

Analgesics: 1. Paracetamol (Acetaminophen): Paracetamol is generally considered one of the safest analgesics in pediatric patients with hepatic or renal impairment. - While it is safer than many other...

May 13, 2025 5
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Type of fluid

The initial fluid replacement should start immediately with isotonic solution (0.9% sodium chloride or Ringer lactate). The typical volume is 10-20 mL/kg over 20-30 minutes, repeated as needed. Estimate...

April 25, 2025 10
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1. Reconstitution of the Vial Each vial contains 1.5 million units of streptokinase. It's reconstituted in 10 ml of normal saline → each 1 ml contains 150,000 units. 2. Dose for a 10 kg Child Dose...

April 25, 2025 2
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7. If there is cerebral edema and RBSL falls <70, what about rate and type of fluid in these cases and in general? Emergency management: Reduce fluid rate by 1/3 to 1/2 Give 3% hypertonic saline...

April 25, 2025 2
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6. What about monitoring osmolality? If it is still high and there is positive Na trend, can I shift to hypotonic saline or not? No, not immediately. Even with a positive Na trend, if osmolality is still...

April 25, 2025 2
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5. When do we shift to half-normal saline? Only if there is a positive Na trend? Yes. You only shift to 0.45% NaCl if: Sodium is rising or stable, No ongoing hypovolemia, Osmolality is not falling...

April 25, 2025 2
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4. After the 4 to 6 hr in management: The final concentration of saline in IV fluid must be between 0.45 to 0.9 (True or False)? True. After the first few hours, fluid tonicity may be reduced (e.g., to...

April 25, 2025 2
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3. How many mEq/L in isotonic saline? 154 mEq/L.

April 25, 2025 2
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2. During the first 6 hours, if the RBSL falls <300 mg/dL, can we add glucose to normal saline? Yes. Once glucose falls to ~250–300 mg/dL, add 5–10% dextrose to prevent hypoglycemia and support...

April 25, 2025 2
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1. In the first 6 hours, the patient must take isotonic normal saline even if corrected Na is high (True or False)? True. During the initial phase (first 4–6 hours), 0.9% NaCl (normal saline) is recommended...

April 25, 2025 2
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Osmolarity

It looks like you typed the same word twice: osmolarity and osmolarity. Maybe you meant to ask about the difference between: Osmolarity and osmolality? If so, here's the difference: Osmolarity is...

April 24, 2025 10
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Tacrolimus dose in liver transplant

Oral: Immediate release: Initial: 0.15 to 0.2 mg/kg/day divided every 12 hours IV: 0.03 to 0.05 mg/kg/day as a continuous IV infusion. ... Note: Limit parenteral use to patients unable to take enteral...

April 24, 2025 10
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