Author: Hossam Elgnainy

In this scenario, yes, you can typically continue empirical antibiotics if the patient is clinically improving, even if final culture results are pending at 5 days. However, this decision must be guided...

1. Case Improvement and Antibiotic De-escalation Clinical improvement alone is not a definitive indication for de-escalation but should prompt a reassessment of therapy. De-escalation relies on:...

When it comes to dosing medications in preterm infants, maturation really matters. In many neonatal pharmacotherapy protocols, clinicians use postmenstrual age (PMA), or corrected gestational age (cGA),...

When a loading dose is given, the level is typically drawn 6–8 hours after the last dose. For patients on maintenance therapy (without a loading dose), you should wait until steady state is reached—which...

Mannitol should be used only for a short duration (typically no longer than 24 to 48 hours) in the management of elevated ICP. ... Monitoring of ICP and treatment response should employ continuous, bedside...

يا دكتورة طالما بتشيلي الطفل من على الفنت يبقى هتستخدمي جرعة ال extubation Oral, IM, IV: 0.5 mg/kg/dose (maximum dose: 10 mg/dose) administered 6 to...

No, MgSO₄ is not contraindicated. It is used for several indications in neonates and infants, such as: Maintenance nutrition, Hypomagnesemia, Torsades de pointes, ventricular tachycardia, Asthma,...

Airway edema or extubation: Oral, IM, IV: 0.5 mg/kg/dose (maximum dose: 10 mg/dose) administered 6 to 12 hours prior to extubation then every 6 hours for 6 doses (total dexamethasone dose: 3 mg/kg) ......

1. Nebulized Budesonide (Pulmicort) Indications: Chronic Asthma: First-line controller therapy for persistent asthma. Viral-Induced Wheezing (VIW): Reduces exacerbation risk in children ≤5 years....

Generally in this case, you need to assess the clinical significance of both culture results before deciding on antibiotic therapy. Here’s how to approach it: ... 1. Blood Culture: CONS Consider contamination:...

Any sensitivity results yet? What about the history of the patient, and is this his first admission? What about the clinical situation of the patient (CBC, fever, vent, ... etc) ? Is the patient already...

The role of synergistic effect of double beta lactam regimens is very limited to certain situations such as the regimen used in MDR Acinetobacter infections (colistin+meropenem+ampicillin/sulbactam) or...