Susceptible infection (non-CNS), treatment: IV:
Premature neonate: 100 mg ampicillin/kg/day divided every 12 hours; dosing based on a pharmacokinetic analysis of 15 premature neonates using a 1:1 formulation of ampicillin to sulbactam (GA ≤28 weeks: n=6; GA >28 weeks: n=9) (Sutton 1986)
Full-term neonate: 100 mg ampicillin/kg/day divided every 8 hours for ≤8 days was used in 108 neonates (GA ≥37 weeks) (Manzoni 2009)
Hossam Elgnainy Selected answer as best January 14, 2024
In bacteremia/sepsis/streptB
Less28D
Range doses 50_75mg/kg/12hr
More 28D
Range doses 50_75mg/kg/8hr
In meningitis up to 100mg/kg/8hr
Omnia Afifi Edited answer January 14, 2024