what is the maximum dose of Tygacil for neonates ?
Hossam Elgnainy Selected answer as best February 24, 2024
Infants and Children <8 year: Use in patients <8 years is not recommended due to adverse effects on tooth development and uncertain dosing; however, use has been described in scenarios where alternative options were unavailable
Dose:
IV: 1.5 to 2 mg/kg loading dose once, then 1 to 2 mg/kg/dose every 12 hours; maximum dose: 50 mg/dose .
Note: Higher loading doses of up to 4 mg/kg/dose have also been reported to treat multidrug resistant gram-negative bacteria
Ref: lexicomp
Hossam Elgnainy Selected answer as best February 24, 2024