Renal dose adj

When to return to normal dose:

• Not just when S. Creat drops once.
• Return to normal dosing only if:
• S. Creat is stable or decreasing over 48 hours.
• Urine output is normal (generally > 1 mL/kg/hr).
• No ongoing renal hypoperfusion (e.g., no new hypotension, hypoxia, or nephrotoxic exposure).
• Drug level monitoring (if applicable) supports normalization.

…

Suggested practice in your case:

• Since S. Creat dropped to 0.9 then rose again to 1.3, that suggests transient improvement — not sustained recovery.
• Keep renal-adjusted dose until S. Creat is:
• <1.0 and stable for 48 hrs, and
• Clinical signs support renal recovery.