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Solved132 viewsNeonatology

2.5 months old baby was born preterm. Do I need to calculate the corrected age for him to determine the correct medication dosage, or is it okay to use the standard pediatric doses without adjusting for prematurity?”

هو لو بيبي شهرين ونصف وكان بريتيرم

لازم احسبله ال corrected age

علشان احسب الدوز بتاعت الادوية

ولا عادي امشي بالدوز بتاعت البيدياترك

Hossam Elgnainy Selected answer as best February 16, 2025
0

When it comes to dosing medications in preterm infants, maturation really matters. In many neonatal pharmacotherapy protocols, clinicians use postmenstrual age (PMA), or corrected gestational age (cGA), as a surrogate for organ maturity rather than chronological age alone.

A cGA of around 44 weeks is commonly cited as a milestone at which many infants’ metabolic and excretory functions are approaching those of term infants. In practice, many centers start to use standard pediatric dosing regimens once the preterm infant reaches a cGA of 44 weeks. However, this isn’t a universal rule. The decision should also take into account the specific pharmacokinetics and pharmacodynamics of the drug in question.

Hossam Elgnainy Selected answer as best February 16, 2025
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