How to calculate alveofact dose for baby 3 kg ,what is criteria for it
And what is difference between alveofact and survanta
Alveofact and Survanta are both brand names of Beractant
Alveofact (Bovine Surfactant):
1. Dosage: The typical dose is 100 mg of phospholipids per kg of body weight.
2. Concentration: Alveofact is usually supplied at a concentration of 50 mg/mL.
For a 3 kg infant:
– Dose calculation: 100 mg/kg × 3 kg = 300 mg
– Volume to administer: 300 mg ÷ 50 mg/mL = 6 mL
Survanta (Beractant):
1. Dosage: The initial dose is 100 mg of phospholipids per kg of birth weight, with up to three additional doses of 100 mg/kg at 6-hour intervals if needed.
2. Concentration: Survanta is supplied at a concentration of 25 mg/mL.
Differences Between Alveofact and Survanta:
1. Source:
– Alveofact: Extracted from bovine (cow) lungs.
– Survanta: Derived from minced bovine lung.
2. Concentration:
– Alveofact: 50 mg of phospholipids per mL.
– Survanta: 25 mg of phospholipids per mL.
3. Dosage: