Stability of propofol 1% after opening in Picu ?
Is it discarded after opening or after 12 hrs or 6hrs?
And what does administration systems mean?
Can you explain it to me precisely? 
Administration system means the bottle, IV bag, lines, cannulas, etc. which used to administer the medication.
For Undiluted: Administration should begin immediately and completed within 12 hours after the vial has been opened.
Do not use if there is evidence of separation of phases of emulsion.
May be further diluted in D5W or NS to a concentration of ≥2 mg/mL;
diluted emulsion is more stable in glass (stability in plastic: 95% potency after 2 hours).
To reduce pain associated with administration, may add lidocaine to propofol immediately before administration in a quantity not to exceed 20 mg lidocaine per 200 mg propofol.
Strict aseptic technique must be maintained in handling.
Prepare drug for single-patient use only. Shake emulsion well before use.
For diluted or admixed: Administration should begin immediately and completed within 6 hours.
